Deployment - Enforce and Detection Servers

Hi,

I understand the below based off documentation.

• ​Single Tier Install: The Oracle Database Server, the Enforce Management Server and a Detection Server are all installed on the same system 
• Two Tier Install: The Oracle Database, Enforce Server on the same box and the Detection Server(s) on a separate box(es)
• Three Tier: Each portion is on a seperate system

What I'd like to know is if I can have the follwing as a hybird:

Enforce/& one Detection Server on the same host

Database on seperate host

Three Detection Servers installed on seperate hosts

Is their any reprecussions and is it even doable? I have my reasons of doing this due conflicts, hence needing this answered.

Thanks!